7MD3

The F1 region of apoptolidin-bound Saccharomyces cerevisiae ATP synthase

This is a non-PDB format compatible entry.

Summary for 7MD3

• Entry DOI: 10.2210/pdb7md3/pdb
• EMDB information: 23764
• Descriptor: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit gamma, ... (8 entities in total)
• Functional Keywords: f1-atpase, inhibitor, anti-cancer, hydrolase, translocase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 8
• Total formula weight: 358659.77

Authors

Guo, H.,Rubinstein, J.L. (deposition date: 2021-04-03, release date: 2021-08-11, Last modification date: 2025-05-14)

• Primary citation: Reisman, B.J.,Guo, H.,Ramsey, H.E.,Wright, M.T.,Reinfeld, B.I.,Ferrell, P.B.,Sulikowski, G.A.,Rathmell, W.K.,Savona, M.R.,Plate, L.,Rubinstein, J.L.,Bachmann, B.O.; A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia; Biorxiv, 2021; DOI: 10.1101/2021.05.31.445492

Experimental method

ELECTRON MICROSCOPY (3.3 Å)