7MAK
HIV-1 Protease (I84V) in Complex with PU7 (LR3-67)
Summary for 7MAK
Entry DOI | 10.2210/pdb7mak/pdb |
Descriptor | Protease, SULFATE ION, diethyl [(4-{(2S,3R)-4-{(2-ethylbutyl)[(4-methoxyphenyl)sulfonyl]amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate, ... (4 entities in total) |
Functional Keywords | hiv, nl4-3 protease, drug resistance, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 (HIV-1) |
Total number of polymer chains | 2 |
Total formula weight | 22872.77 |
Authors | Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-20, Last modification date: 2023-10-18) |
Primary citation | Lockbaum, G.J.,Schiffer, C.A. HIV-1 Protease in Complex with ligands To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.972 Å) |
Structure validation
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