7M9S

HIV-1 Protease WT (NL4-3) in Complex with NR01-141

Summary for 7M9S

• Entry DOI: 10.2210/pdb7m9s/pdb
• Descriptor: Protease, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, ... (4 entities in total)
• Functional Keywords: hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 22732.69

Authors

Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-08-31, Last modification date: 2023-10-18)

• Primary citation: Lockbaum, G.J.,Schiffer, C.A.; HIV-1 Protease WT (NL4-3) in Complex with NR01-141; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.961 Å)