7M9R

HIV-1 Protease WT (NL4-3) in Complex with LR4-44

Summary for 7M9R

• Entry DOI: 10.2210/pdb7m9r/pdb
• Descriptor: Protease, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-[{4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]butan-2-yl}carbamate, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 22564.54

Authors

Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-06, Last modification date: 2023-10-18)

• Primary citation: Lockbaum, G.J.,Schiffer, C.A.; HIV-1 Protease WT (NL4-3) in Complex with LR4-44; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.891 Å)