7M9Q
HIV-1 Protease WT (NL4-3) in Complex with LR4-33
Summary for 7M9Q
Entry DOI | 10.2210/pdb7m9q/pdb |
Descriptor | Protease, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-[{4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]-1-{4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl}butan-2-yl]carbamate, ... (4 entities in total) |
Functional Keywords | hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 (HIV-1) |
Total number of polymer chains | 2 |
Total formula weight | 22847.85 |
Authors | Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-06, Last modification date: 2023-10-18) |
Primary citation | Lockbaum, G.J.,Schiffer, C.A. HIV-1 Protease WT (NL4-3) in Complex with LR4-33 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.952 Å) |
Structure validation
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