7M81
Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 100 s
Summary for 7M81
Entry DOI | 10.2210/pdb7m81/pdb |
Descriptor | DNA polymerase eta, DNA (5'-D(*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*A)-3'), ... (9 entities in total) |
Functional Keywords | dna polymerase, time resolved crystallography, deprotonation, dna binding protein, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 55668.05 |
Authors | Gregory, M.T.,Gao, Y.,Yang, W. (deposition date: 2021-03-29, release date: 2021-06-02, Last modification date: 2023-10-18) |
Primary citation | Gregory, M.T.,Gao, Y.,Cui, Q.,Yang, W. Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34088846DOI: 10.1073/pnas.2103990118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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