7M5Y
human ATP13A2 in the outward-facing E2 state bound to spermine and magnesium fluoride
Summary for 7M5Y
Entry DOI | 10.2210/pdb7m5y/pdb |
EMDB information | 23685 |
Descriptor | Polyamine-transporting ATPase 13A2, 2-acetamido-2-deoxy-beta-D-glucopyranose, SPERMINE (FULLY PROTONATED FORM), ... (13 entities in total) |
Functional Keywords | ion transport inhibited state, membrane protein, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 136398.52 |
Authors | Lee, K.P.K. (deposition date: 2021-03-25, release date: 2022-03-30, Last modification date: 2022-04-27) |
Primary citation | Tillinghast, J.,Drury, S.,Bowser, D.,Benn, A.,Lee, K.P.K. Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2. Mol.Cell, 81:4650-4662.e4, 2021 Cited by PubMed: 34715014DOI: 10.1016/j.molcel.2021.10.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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