7M33

The structure of Bacillus subtilis BmrCD in the inward-facing conformation bound to Hoechst-33342 and ATP

Summary for 7M33

Entry DOI	10.2210/pdb7m33/pdb
EMDB information	23641
Descriptor	Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	abc transporter, multi-drug efflux transporter, abc exporter, transport protein
Biological source	Bacillus subtilis subsp. subtilis str. 168 More
Total number of polymer chains	2
Total formula weight	146892.32
Authors	Thaker, T.M.,Tomasiak, T.M. (deposition date: 2021-03-18, release date: 2022-01-05, Last modification date: 2024-05-29)
Primary citation	Thaker, T.M.,Mishra, S.,Zhou, W.,Mohan, M.,Tang, Q.,Faraldo-Gomez, J.D.,Mchaourab, H.S.,Tomasiak, T.M. Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter. Nat.Chem.Biol., 18:226-235, 2022 Cited by PubMed: 34931066 DOI: 10.1038/s41589-021-00936-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.55 Å)

Structure validation