7LZE

Cryo-EM Structure of disulfide stabilized HMPV F v4-B

7LZE の概要

• エントリーDOI: 10.2210/pdb7lze/pdb
• EMDBエントリー: 23605
• 分子名称: Fusion glycoprotein F0, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: hmpv f, postfusion, prefusion, viral protein, immunization
• 由来する生物種: Human metapneumovirus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 165358.36

構造登録者

Gorman, J.,Kwong, P.D. (登録日: 2021-03-09, 公開日: 2021-08-25, 最終更新日: 2021-10-06)

• 主引用文献: Stewart-Jones, G.B.E.,Gorman, J.,Ou, L.,Zhang, B.,Joyce, M.G.,Yang, L.,Cheng, C.,Chuang, G.Y.,Foulds, K.E.,Kong, W.P.,Olia, A.S.,Sastry, M.,Shen, C.H.,Todd, J.P.,Tsybovsky, Y.,Verardi, R.,Yang, Y.,Collins, P.L.,Corti, D.,Lanzavecchia, A.,Scorpio, D.G.,Mascola, J.R.,Buchholz, U.J.,Kwong, P.D.; Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34551978; DOI: 10.1073/pnas.2106196118

実験手法

ELECTRON MICROSCOPY (3.23 Å)