7LXN

Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122

7LXN の概要

• エントリーDOI: 10.2210/pdb7lxn/pdb
• EMDBエントリー: 23572
• 分子名称: HIV-1 Env glycoprotein gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: env, sosip, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 394585.70

構造登録者

Martin, G.M.,Ward, A.B.,Sattentau, Q.J. (登録日: 2021-03-04, 公開日: 2022-03-09, 最終更新日: 2023-09-20)

• 主引用文献: Martin, G.M.,Russell, R.A.,Mundsperger, P.,Harris, S.,Jovanoska, L.,Trajano, L.F.,Schiffner, T.,Fabian, K.,Tolazzi, M.,Scarlatti, G.,McFarlane, L.,Cheeseman, H.,Aldon, Y.,Schermer, E.E.,Breemen, M.,Sliepen, K.,Katinger, D.,Kunert, R.,Sanders, R.W.,Shattock, R.,Ward, A.B.,Sattentau, Q.J.; Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.; Npj Vaccines, 8:101-101, 2023; PubMed: 37443366; DOI: 10.1038/s41541-023-00696-w

実験手法

ELECTRON MICROSCOPY (3.85 Å)