7LVP

Cryptococcus neoformans AIR synthetase

Summary for 7LVP

• Entry DOI: 10.2210/pdb7lvp/pdb
• Related: 7LVO
• Descriptor: AIR synthase, 1,2-ETHANEDIOL, SUCCINIC ACID, ... (6 entities in total)
• Functional Keywords: air synthetase, phosphoribosyl-aminoimidazole synthetase, phosphoribosylaminoimidazole synthetase, biosynthetic protein, ligase
• Biological source: Cryptococcus neoformans var. grubii serotype A (Filobasidiella neoformans var. grubii)
• Total number of polymer chains: 1
• Total formula weight: 36238.97

Authors

Chua, S.M.H.,Luo, Z.,Lim, B.Y.J.,Kobe, B.,Fraser, J.A. (deposition date: 2021-02-26, release date: 2021-08-25, Last modification date: 2023-10-18)

• Primary citation: Chua, S.M.H.,Wizrah, M.S.I.,Luo, Z.,Lim, B.Y.J.,Kappler, U.,Kobe, B.,Fraser, J.A.; Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.; J.Biol.Chem., 297:101091-101091, 2021; PubMed: 34416230; DOI: 10.1016/j.jbc.2021.101091

Experimental method

X-RAY DIFFRACTION (2.24 Å)