7LVO

Cryptococcus neoformans GAR synthetase

Summary for 7LVO

Entry DOI	10.2210/pdb7lvo/pdb
Descriptor	phosphoribosyl-glycinamide (GAR) synthetase, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	gar synthetase, phosphoribosyl-glycinamide synthetase, phosphoribosylglycinamide synthetase, biosynthetic protein, ligase
Biological source	Cryptococcus neoformans var. grubii serotype A (Filobasidiella neoformans var. grubii)
Total number of polymer chains	1
Total formula weight	50956.80
Authors	Chua, S.M.H.,Luo, Z.,Lim, B.Y.J.,Kobe, B.,Fraser, J.A. (deposition date: 2021-02-26, release date: 2021-08-25, Last modification date: 2023-10-18)
Primary citation	Chua, S.M.H.,Wizrah, M.S.I.,Luo, Z.,Lim, B.Y.J.,Kappler, U.,Kobe, B.,Fraser, J.A. Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets. J.Biol.Chem., 297:101091-101091, 2021 Cited by PubMed: 34416230 DOI: 10.1016/j.jbc.2021.101091 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation