7LV5
The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and L-Histidine at the enzyme beta-site at 1.55 Angstrom resolution
Summary for 7LV5
Entry DOI | 10.2210/pdb7lv5/pdb |
Descriptor | Tryptophan synthase alpha chain, BICINE, HISTIDINE, ... (13 entities in total) |
Functional Keywords | inhibitor, internal aldimine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 73809.25 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-02-23, release date: 2022-03-02, Last modification date: 2023-10-18) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J. The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and L-Histidine at the enzyme beta-site at 1.55 Angstrom resolution To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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