7LV5

The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and L-Histidine at the enzyme beta-site at 1.55 Angstrom resolution

Summary for 7LV5

• Entry DOI: 10.2210/pdb7lv5/pdb
• Descriptor: Tryptophan synthase alpha chain, BICINE, HISTIDINE, ... (13 entities in total)
• Functional Keywords: inhibitor, internal aldimine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 73809.25

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-02-23, release date: 2022-03-02, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and L-Histidine at the enzyme beta-site at 1.55 Angstrom resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)