7LV3

Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state

7LV3 の概要

• エントリーDOI: 10.2210/pdb7lv3/pdb
• 分子名称: Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• 機能のキーワード: protein kinase g, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 141141.43

構造登録者

Sharma, R.,Lying, Q.,Casteel, D.,Kim, C. (登録日: 2021-02-23, 公開日: 2022-08-24, 最終更新日: 2023-10-18)

• 主引用文献: Sharma, R.,Kim, J.J.,Qin, L.,Henning, P.,Akimoto, M.,VanSchouwen, B.,Kaur, G.,Sankaran, B.,MacKenzie, K.R.,Melacini, G.,Casteel, D.E.,Herberg, F.W.,Kim, C.W.; An auto-inhibited state of protein kinase G and implications for selective activation.; Elife, 11:-, 2022; PubMed: 35929723; DOI: 10.7554/eLife.79530

実験手法

X-RAY DIFFRACTION (2.41 Å)