7LUH

Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment bromophenoxy propanamide

7LUH の概要

• エントリーDOI: 10.2210/pdb7luh/pdb
• 分子名称: Thiol:disulfide interchange protein, (2~{R})-2-(4-bromanylphenoxy)propanamide (3 entities in total)
• 機能のキーワード: bpsdsba, fragment, cryptic-pocket, oxidoreductase
• 由来する生物種: Burkholderia pseudomallei (strain K96243)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22266.20

構造登録者

Petit, G.A.,Martin, J.L.,McMahon, R.M. (登録日: 2021-02-22, 公開日: 2022-01-05, 最終更新日: 2023-10-18)

• 主引用文献: Petit, G.A.,Mohanty, B.,McMahon, R.M.,Nebl, S.,Hilko, D.H.,Wilde, K.L.,Scanlon, M.J.,Martin, J.L.,Halili, M.A.; Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA.; Acta Crystallogr D Struct Biol, 78:75-90, 2022; PubMed: 34981764; DOI: 10.1107/S2059798321011475

実験手法

X-RAY DIFFRACTION (1.84 Å)