7LQZ
Structure of squirrel TRPV1 in complex with RTX
Summary for 7LQZ
| Entry DOI | 10.2210/pdb7lqz/pdb |
| Related | 7LQY |
| EMDB information | 23491 23492 |
| Descriptor | Osm-9-like TRP channel 1, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, resiniferatoxin, ... (4 entities in total) |
| Functional Keywords | transient receptor potential v family member 1, trp channel, trpv1 full length, trpv1 wild type, rtx, resiniferatoxin, membrane protein |
| Biological source | Ictidomys tridecemlineatus (Thirteen-lined ground squirrel, Spermophilus tridecemlineatus) |
| Total number of polymer chains | 4 |
| Total formula weight | 410471.38 |
| Authors | Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. (deposition date: 2021-02-15, release date: 2021-04-21, Last modification date: 2024-03-06) |
| Primary citation | Nadezhdin, K.D.,Neuberger, A.,Nikolaev, Y.A.,Murphy, L.A.,Gracheva, E.O.,Bagriantsev, S.N.,Sobolevsky, A.I. Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12:2154-2154, 2021 Cited by PubMed: 33846324DOI: 10.1038/s41467-021-22507-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.41 Å) |
Structure validation
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