7LO7

NorA in complex with Fab25

Summary for 7LO7

Entry DOI	10.2210/pdb7lo7/pdb
EMDB information	23463
Descriptor	Quinolone resistance protein NorA, Fab25 Heavy Chain, Fab25 Light Chain (3 entities in total)
Functional Keywords	efflux pump, antibiotic resistance, transport protein
Biological source	Staphylococcus aureus More
Total number of polymer chains	3
Total formula weight	96363.79
Authors	Brawley, D.N.,Sauer, D.B.,Song, J.M.,Koide, A.,Koide, S.,Traaseth, N.J.,Wang, D.N. (deposition date: 2021-02-09, release date: 2022-04-20, Last modification date: 2024-10-16)
Primary citation	Brawley, D.N.,Sauer, D.B.,Li, J.,Zheng, X.,Koide, A.,Jedhe, G.S.,Suwatthee, T.,Song, J.,Liu, Z.,Arora, P.S.,Koide, S.,Torres, V.J.,Wang, D.N.,Traaseth, N.J. Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus. Nat.Chem.Biol., 18:706-712, 2022 Cited by PubMed: 35361990 DOI: 10.1038/s41589-022-00994-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.74 Å)

Structure validation