7LNQ
Structure of the avibactam-CDD-1 3 minute complex in imidazole and MPD
Summary for 7LNQ
Entry DOI | 10.2210/pdb7lnq/pdb |
Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, CARBON DIOXIDE, ... (6 entities in total) |
Functional Keywords | beta-lactamase, antibiotic resistance, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Clostridioides difficile |
Total number of polymer chains | 1 |
Total formula weight | 36856.75 |
Authors | Smith, C.A.,Vakulenko, S.B.,Stewart, N.K. (deposition date: 2021-02-08, release date: 2021-05-12, Last modification date: 2023-11-15) |
Primary citation | Stewart, N.K.,Toth, M.,Stasyuk, A.,Vakulenko, S.B.,Smith, C.A. In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7:1765-1776, 2021 Cited by PubMed: 33908775DOI: 10.1021/acsinfecdis.1c00094 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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