7LNO

Structure of apo-CDD-1 beta-lactamase in imidazole and MPD

Summary for 7LNO

Entry DOI	10.2210/pdb7lno/pdb
Descriptor	Beta-lactamase, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywords	beta-lactamase, antibiotic resistance, hydrolase
Biological source	Clostridioides difficile
Total number of polymer chains	1
Total formula weight	36833.67
Authors	Smith, C.A.,Vakulenko, S.B.,Stewart, N.K. (deposition date: 2021-02-08, release date: 2021-05-12, Last modification date: 2023-11-15)
Primary citation	Stewart, N.K.,Toth, M.,Stasyuk, A.,Vakulenko, S.B.,Smith, C.A. In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7:1765-1776, 2021 Cited by PubMed: 33908775 DOI: 10.1021/acsinfecdis.1c00094 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation