7LES

Acanthamoeba castellanii CYP51 (AcCYP51)-Imidazole complex

7LES の概要

• エントリーDOI: 10.2210/pdb7les/pdb
• 分子名称: Obtusifoliol 14alphademethylase, putative, PROTOPORPHYRIN IX CONTAINING FE, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• 機能のキーワード: cyp51, ergosterol biosynthesis, acanthamoeba, 14-alpha-demethylase, oxidoreductase
• 由来する生物種: Acanthamoeba castellanii str. Neff
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 213306.38

構造登録者

Sharma, V.,Podust, L.M. (登録日: 2021-01-15, 公開日: 2021-12-22, 最終更新日: 2023-10-18)

• 主引用文献: Nienhaus, K.,Sharma, V.,Nienhaus, G.U.,Podust, L.M.; Homodimerization Counteracts the Detrimental Effect of Nitrogenous Heme Ligands on the Enzymatic Activity of Acanthamoeba castellanii CYP51.; Biochemistry, 61:1363-1377, 2022; PubMed: 35730528; DOI: 10.1021/acs.biochem.2c00198

実験手法

X-RAY DIFFRACTION (2.65 Å)