7L7T

BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A)

7L7T の概要

• エントリーDOI: 10.2210/pdb7l7t/pdb
• EMDBエントリー: 23218
• 分子名称: BG505 SOSIP.v5.2(7S) - gp120, BG505 SOSIP.v5.2(7S) - gp41, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hiv, vaccine design, protein design, nanoparticles, bg505, viral protein
• 由来する生物種: Human immunodeficiency virus 1 (HIV-1); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 241298.53

構造登録者

Antanasijevic, A.,Cannac, F.,Sewall, L.M.,Ward, A.B. (登録日: 2020-12-30, 公開日: 2021-08-04, 最終更新日: 2021-08-25)

• 主引用文献: Antanasijevic, A.,Sewall, L.M.,Cottrell, C.A.,Carnathan, D.G.,Jimenez, L.E.,Ngo, J.T.,Silverman, J.B.,Groschel, B.,Georgeson, E.,Bhiman, J.,Bastidas, R.,LaBranche, C.,Allen, J.D.,Copps, J.,Perrett, H.R.,Rantalainen, K.,Cannac, F.,Yang, Y.R.,de la Pena, A.T.,Rocha, R.F.,Berndsen, Z.T.,Baker, D.,King, N.P.,Sanders, R.W.,Moore, J.P.,Crotty, S.,Crispin, M.,Montefiori, D.C.,Burton, D.R.,Schief, W.R.,Silvestri, G.,Ward, A.B.; Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.; Nat Commun, 12:4817-4817, 2021; PubMed: 34376662; DOI: 10.1038/s41467-021-25087-4

実験手法

ELECTRON MICROSCOPY (3.7 Å)