7L6T
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and two Magnesium (Mg) ions.
7L6T の概要
エントリーDOI | 10.2210/pdb7l6t/pdb |
分子名称 | 2'-O-methyltransferase, beta-D-fructopyranose, Non-structural protein 10, ... (11 entities in total) |
機能のキーワード | structural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein, sah, cap-1, viral protein-rna complex, viral protein/rna |
由来する生物種 | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2) 詳細 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 52084.77 |
構造登録者 | Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Kiryukhina, O.,Brunzelle, J.S.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2020-12-23, 公開日: 2021-01-06, 最終更新日: 2024-03-06) |
主引用文献 | Minasov, G.,Rosas-Lemus, M.,Shuvalova, L.,Inniss, N.L.,Brunzelle, J.S.,Daczkowski, C.M.,Hoover, P.,Mesecar, A.D.,Satchell, K.J.F. Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2'- O -methyl transfer by SARS-CoV-2 nsp16. Sci.Signal., 14:-, 2021 Cited by PubMed: 34131072DOI: 10.1126/scisignal.abh2071 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.78 Å) |
構造検証レポート
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