7KX9

Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA-target complex

Summary for 7KX9

• Entry DOI: 10.2210/pdb7kx9/pdb
• Related: 7KX7
• EMDB information: 23061 23063
• Descriptor: Piwi-A, RNA (5'-R(P*UP*CP*UP*CP*UP*UP*GP*AP*GP*UP*UP*GP*GP*AP*CP*AP*AP*AP*UP*GP*GP*CP*AP*(OMG))-3'), RNA (5'-R(P*UP*GP*UP*CP*CP*AP*AP*CP*UP*CP*AP*AP*GP*AP*GP*A)-3'), ... (4 entities in total)
• Functional Keywords: rnaseh, protein-rna complex, rna binding protein, pirna binding, paz piwi domain protein, hydrolase, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Ephydatia fluviatilis; More
• Total number of polymer chains: 3
• Total formula weight: 101110.96

Authors

Anzelon, T.A.,Chowdhury, S.,Lander, G.C.,MacRae, I.J. (deposition date: 2020-12-03, release date: 2021-07-14, Last modification date: 2024-05-29)

• Primary citation: Anzelon, T.A.,Chowdhury, S.,Hughes, S.M.,Xiao, Y.,Lander, G.C.,MacRae, I.J.; Structural basis for piRNA targeting.; Nature, 597:285-289, 2021; PubMed: 34471284; DOI: 10.1038/s41586-021-03856-x

Experimental method

ELECTRON MICROSCOPY (3.5 Å)