7KWP
Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and L-lysine bound at the allosteric site in C2221 space group
Summary for 7KWP
Entry DOI | 10.2210/pdb7kwp/pdb |
Descriptor | 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | lyase |
Biological source | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) |
Total number of polymer chains | 6 |
Total formula weight | 206707.18 |
Authors | Saran, S.,Sanders, D.A.R. (deposition date: 2020-12-01, release date: 2021-12-08, Last modification date: 2023-11-29) |
Primary citation | Saran, S.,Sanders, D.A.R. B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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