7KW2

Non-ribosomal didomain (holo-PCP-C) acceptor bound state, R2577G

Summary for 7KW2

• Entry DOI: 10.2210/pdb7kw2/pdb
• Descriptor: PCP-C didomain, 4'-PHOSPHOPANTETHEINE (3 entities in total)
• Functional Keywords: nrps, c-domain, pcp-domain, biosynthetic protein
• Biological source: Thermobifida fusca
• Total number of polymer chains: 2
• Total formula weight: 115492.31

Authors

Izore, T.,Ho, Y.T.C.,Kaczmarski, J.A.,Gavriilidou, A.,Chow, K.H.,Steer, D.,Goode, R.J.A.,Schittenhelm, R.B.,Tailhades, J.,Tosin, M.,Challis, G.L.,Krenske, E.H.,Ziemert, N.,Jackson, C.J.,Cryle, M.J. (deposition date: 2020-11-29, release date: 2021-03-24, Last modification date: 2024-04-03)

• Primary citation: Izore, T.,Candace Ho, Y.T.,Kaczmarski, J.A.,Gavriilidou, A.,Chow, K.H.,Steer, D.L.,Goode, R.J.A.,Schittenhelm, R.B.,Tailhades, J.,Tosin, M.,Challis, G.L.,Krenske, E.H.,Ziemert, N.,Jackson, C.J.,Cryle, M.J.; Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.; Nat Commun, 12:2511-2511, 2021; PubMed: 33947858; DOI: 10.1038/s41467-021-22623-0

Experimental method

X-RAY DIFFRACTION (2 Å)