7KVV

Crystal structure of Squash RNA aptamer in complex with DFHBI-1T

7KVV の概要

• エントリーDOI: 10.2210/pdb7kvv/pdb
• 分子名称: Squash RNA aptamer bound to DFHO, MAGNESIUM ION, (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, ... (4 entities in total)
• 機能のキーワード: fluorogenic aptamer, adenine riboswitch, rna
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27316.73

構造登録者

Truong, L.,Ferre-D'Amare, A.R. (登録日: 2020-11-28, 公開日: 2022-01-19, 最終更新日: 2023-10-18)

• 主引用文献: Truong, L.,Kooshapur, H.,Dey, S.K.,Li, X.,Tjandra, N.,Jaffrey, S.R.,Ferre-D'Amare, A.R.; The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.; Nat.Chem.Biol., 18:191-198, 2022; PubMed: 34937911; DOI: 10.1038/s41589-021-00931-2

実験手法

X-RAY DIFFRACTION (2.85 Å)