7KVT

Crystal structure of Squash RNA aptamer in complex with DFHBI-1T with iridium (III) ions

Summary for 7KVT

• Entry DOI: 10.2210/pdb7kvt/pdb
• Descriptor: Squash RNA aptamer bound to DFHBI-1T with iridium (III) ions, (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, IRIDIUM HEXAMMINE ION, ... (5 entities in total)
• Functional Keywords: fluorogenic aptamer, adenine riboswitch, rna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 28238.93

Authors

Truong, L.,Ferre-D'Amare, A.R. (deposition date: 2020-11-28, release date: 2022-01-19, Last modification date: 2024-05-22)

• Primary citation: Truong, L.,Kooshapur, H.,Dey, S.K.,Li, X.,Tjandra, N.,Jaffrey, S.R.,Ferre-D'Amare, A.R.; The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.; Nat.Chem.Biol., 18:191-198, 2022; PubMed: 34937911; DOI: 10.1038/s41589-021-00931-2

Experimental method

X-RAY DIFFRACTION (2.73 Å)