7KUS
Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N8-Acetylspermidine (Tetrahedral Intermediate)
Summary for 7KUS
Entry DOI | 10.2210/pdb7kus/pdb |
Descriptor | Polyamine deacetylase HDAC10, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL, ... (8 entities in total) |
Functional Keywords | histone deacetylase, hydrolase |
Biological source | Danio rerio (Zebrafish) |
Total number of polymer chains | 1 |
Total formula weight | 76192.85 |
Authors | Herbst-Gervasoni, C.J.,Christianson, D.W. (deposition date: 2020-11-25, release date: 2021-02-03, Last modification date: 2023-10-18) |
Primary citation | Herbst-Gervasoni, C.J.,Christianson, D.W. X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60:303-313, 2021 Cited by PubMed: 33449614DOI: 10.1021/acs.biochem.0c00936 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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