7KTO

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56A mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site

Summary for 7KTO

• Entry DOI: 10.2210/pdb7kto/pdb
• Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, ... (9 entities in total)
• Functional Keywords: lyase
• Biological source: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
• Total number of polymer chains: 6
• Total formula weight: 208935.12

Authors

Saran, S.,Sanders, D.A.R. (deposition date: 2020-11-24, release date: 2021-12-01, Last modification date: 2023-11-29)

• Primary citation: Saran, S.,Skovpen, Y.,Yazdi, M.M.,Palmer, D.R.J.,Sanders, D.A.R.; ALLOSTERIC SITE RESIDUE 'H56' CAPS THE INHIBITOR AT THE TIGHT DIMER INTERFACE FOR TRANSMITTING THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.13 Å)