7KTN
DNA Polymerase Mu, 8-oxodGTP:At Product State Ternary Complex, 10 mM Mg2+ (2160min)
Summary for 7KTN
Entry DOI | 10.2210/pdb7ktn/pdb |
Descriptor | DNA-directed DNA/RNA polymerase mu, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... (11 entities in total) |
Functional Keywords | time-lapse crystallography, oxidized nucleotide insertion, dna polymerase mu, double strand break repair, replication |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 46207.60 |
Authors | Jamsen, J.A.,Wilson, S.H. (deposition date: 2020-11-24, release date: 2021-12-15, Last modification date: 2023-10-18) |
Primary citation | Jamsen, J.A.,Sassa, A.,Shock, D.D.,Beard, W.A.,Wilson, S.H. Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12:2059-2059, 2021 Cited by PubMed: 33824325DOI: 10.1038/s41467-021-21354-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.33 Å) |
Structure validation
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