7KTH
DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mg2+ (2160min)
Summary for 7KTH
Entry DOI | 10.2210/pdb7kth/pdb |
Descriptor | DNA-directed DNA/RNA polymerase mu, 1,2-ETHANEDIOL, CHLORIDE ION, ... (12 entities in total) |
Functional Keywords | time-lapse crystallography, oxidized nucleotide insertion, dna polymerase mu, double strand break repair, replication |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 46383.76 |
Authors | Jamsen, J.A.,Wilson, S.H. (deposition date: 2020-11-24, release date: 2022-05-11, Last modification date: 2024-04-03) |
Primary citation | Jamsen, J.A.,Sassa, A.,Shock, D.D.,Beard, W.A.,Wilson, S.H. Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12:2059-2059, 2021 Cited by PubMed: 33824325DOI: 10.1038/s41467-021-21354-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.476 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)