7KTB

DNA Polymerase Mu, 8-oxodGTP:Ct Reaction State Ternary Complex, 10 mM Mn2+ (40min)

Summary for 7KTB

Entry DOI	10.2210/pdb7ktb/pdb
Descriptor	DNA-directed DNA/RNA polymerase mu, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, PYROPHOSPHATE, ... (12 entities in total)
Functional Keywords	time-lapse crystallography, oxidized nucleotide insertion, dna polymerase mu, double strand break repair, replication
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	47420.56
Authors	Jamsen, J.A.,Wilson, S.H. (deposition date: 2020-11-24, release date: 2022-05-11, Last modification date: 2023-10-18)
Primary citation	Jamsen, J.A.,Sassa, A.,Shock, D.D.,Beard, W.A.,Wilson, S.H. Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12:2059-2059, 2021 Cited by PubMed: 33824325 DOI: 10.1038/s41467-021-21354-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.576 Å)

Structure validation