7KQT
A 1.84-A resolution crystal structure of heme-dependent L-tyrosine hydroxylase in complex with 3-fluoro-L-tyrosine and cyanide
Summary for 7KQT
Entry DOI | 10.2210/pdb7kqt/pdb |
Descriptor | Heme-dependent L-tyrosine hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, 3-FLUOROTYROSINE, ... (6 entities in total) |
Functional Keywords | heme-binding enzyme, l-tyrosine hydroxylase, oxidoreductase |
Biological source | Streptomyces sclerotialus |
Total number of polymer chains | 2 |
Total formula weight | 71051.69 |
Authors | |
Primary citation | Wang, Y.,Davis, I.,Shin, I.,Xu, H.,Liu, A. Molecular Rationale for Partitioning between C-H and C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase. J.Am.Chem.Soc., 143:4680-4693, 2021 Cited by PubMed: 33734681DOI: 10.1021/jacs.1c00175 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.835 Å) |
Structure validation
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