7KQ3

Structure of isethionate sulfite-lyase from Bilophila wadsworthia with substrate isethionate bound

Summary for 7KQ3

Entry DOI	10.2210/pdb7kq3/pdb
Descriptor	Isethionate sulfite-lyase, 2-hydroxyethylsulfonic acid (3 entities in total)
Functional Keywords	glycyl radical enzyme, isethionate-sulfite lyase, carbon-sulfur bond cleavage, microbiome, lyase
Biological source	Bilophila wadsworthia (strain 3_1_6)
Total number of polymer chains	4
Total formula weight	376831.31
Authors	Dawson, C.D.,Backman, L.R.F.,Drennan, C.L. (deposition date: 2020-11-13, release date: 2021-04-07, Last modification date: 2023-10-18)
Primary citation	Dawson, C.D.,Irwin, S.M.,Backman, L.R.F.,Le, C.,Wang, J.X.,Vennelakanti, V.,Yang, Z.,Kulik, H.J.,Drennan, C.L.,Balskus, E.P. Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase. Cell Chem Biol, 28:1333-, 2021 Cited by PubMed: 33773110 DOI: 10.1016/j.chembiol.2021.03.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.688 Å)

Structure validation