7KQ3

Structure of isethionate sulfite-lyase from Bilophila wadsworthia with substrate isethionate bound

7KQ3 の概要

• エントリーDOI: 10.2210/pdb7kq3/pdb
• 分子名称: Isethionate sulfite-lyase, 2-hydroxyethylsulfonic acid (3 entities in total)
• 機能のキーワード: glycyl radical enzyme, isethionate-sulfite lyase, carbon-sulfur bond cleavage, microbiome, lyase
• 由来する生物種: Bilophila wadsworthia (strain 3_1_6)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 376831.31

構造登録者

Dawson, C.D.,Backman, L.R.F.,Drennan, C.L. (登録日: 2020-11-13, 公開日: 2021-04-07, 最終更新日: 2023-10-18)

• 主引用文献: Dawson, C.D.,Irwin, S.M.,Backman, L.R.F.,Le, C.,Wang, J.X.,Vennelakanti, V.,Yang, Z.,Kulik, H.J.,Drennan, C.L.,Balskus, E.P.; Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.; Cell Chem Biol, 28:1333-, 2021; PubMed: 33773110; DOI: 10.1016/j.chembiol.2021.03.001

実験手法

X-RAY DIFFRACTION (2.688 Å)