7KOJ

The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder494 inhibitor

Summary for 7KOJ

• Entry DOI: 10.2210/pdb7koj/pdb
• Related: 6WZU 6wrh
• Descriptor: Papain-like protease, 2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]-5-{[(prop-2-en-1-yl)carbamoyl]amino}benzamide, ZINC ION, ... (8 entities in total)
• Functional Keywords: covid-19, coronavirus, sars, cov-2, papain-like protease, idp51000, idp52003, center for structural genomics of infectious diseases, csgid, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 1
• Total formula weight: 36996.49

Authors

Osipiuk, J.,Tesar, C.,Endres, M.,Lisnyak, V.,Maki, S.,Taylor, C.,Zhang, Y.,Zhou, Z.,Azizi, S.A.,Jones, K.,Kathayat, R.,Snyder, S.A.,Dickinson, B.C.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-11-09, release date: 2020-11-18, Last modification date: 2023-10-18)

• Primary citation: Osipiuk, J.,Tesar, C.,Endres, M.,Lisnyak, V.,Maki, S.,Taylor, C.,Zhang, Y.,Zhou, Z.,Azizi, S.A.,Jones, K.,Kathayat, R.,Snyder, S.A.,Dickinson, B.C.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder494; to be published,

Experimental method

X-RAY DIFFRACTION (2.02 Å)