7KFH

Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437

7KFH の概要

• エントリーDOI: 10.2210/pdb7kfh/pdb
• EMDBエントリー: 22853
• 分子名称: Virion spike glycoprotein 1, Antibody Fab EBOV-437 light chain, Virion spike glycoprotein 2, ... (7 entities in total)
• 機能のキーワード: ebolavirus, glycan cap, antibody, broadly neutralizing, filovirus, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Ebola virus; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 323635.68

構造登録者

Murin, C.D.,Ward, A.B. (登録日: 2020-10-13, 公開日: 2021-04-28)

• 主引用文献: Murin, C.D.,Gilchuk, P.,Ilinykh, P.A.,Huang, K.,Kuzmina, N.,Shen, X.,Bruhn, J.F.,Bryan, A.L.,Davidson, E.,Doranz, B.J.,Williamson, L.E.,Copps, J.,Alkutkar, T.,Flyak, A.I.,Bukreyev, A.,Crowe Jr., J.E.,Ward, A.B.; Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.; Cell Rep, 35:108984-108984, 2021; PubMed: 33852862; DOI: 10.1016/j.celrep.2021.108984

実験手法

ELECTRON MICROSCOPY (3.8 Å)