7KEF

RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state

Summary for 7KEF

• Entry DOI: 10.2210/pdb7kef/pdb
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, RNA, ... (16 entities in total)
• Functional Keywords: rna polymerase ii, elongation complex, unnatural base, tpt3, nam, swing state, transcription, transcription-dna-rna complex, transcription/dna/rna
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 13
• Total formula weight: 487623.92

Authors

Oh, J.,Wang, D. (deposition date: 2020-10-10, release date: 2021-06-23, Last modification date: 2023-10-18)

• Primary citation: Oh, J.,Shin, J.,Unarta, I.C.,Wang, W.,Feldman, A.W.,Karadeema, R.J.,Xu, L.,Xu, J.,Chong, J.,Krishnamurthy, R.,Huang, X.,Romesberg, F.E.,Wang, D.; Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.; Nat.Chem.Biol., 17:906-914, 2021; PubMed: 34140682; DOI: 10.1038/s41589-021-00817-3

Experimental method

X-RAY DIFFRACTION (3.89 Å)