7KEF

RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state

7KEF の概要

• エントリーDOI: 10.2210/pdb7kef/pdb
• 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, RNA, ... (16 entities in total)
• 機能のキーワード: rna polymerase ii, elongation complex, unnatural base, tpt3, nam, swing state, transcription, transcription-dna-rna complex, transcription/dna/rna
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 487623.92

構造登録者

Oh, J.,Wang, D. (登録日: 2020-10-10, 公開日: 2021-06-23, 最終更新日: 2023-10-18)

• 主引用文献: Oh, J.,Shin, J.,Unarta, I.C.,Wang, W.,Feldman, A.W.,Karadeema, R.J.,Xu, L.,Xu, J.,Chong, J.,Krishnamurthy, R.,Huang, X.,Romesberg, F.E.,Wang, D.; Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.; Nat.Chem.Biol., 17:906-914, 2021; PubMed: 34140682; DOI: 10.1038/s41589-021-00817-3

実験手法

X-RAY DIFFRACTION (3.89 Å)