7KE4

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-class)

7KE4 の概要

• エントリーDOI: 10.2210/pdb7ke4/pdb
• EMDBエントリー: 22831 22832 22833 22834 22835 22836 22837 22838
• 分子名称: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: sars-cov-2 spike protein trimer, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 440792.14

構造登録者

Gobeil, S.,Acharya, P. (登録日: 2020-10-10, 公開日: 2020-11-04, 最終更新日: 2021-03-31)

• 主引用文献: Gobeil, S.M.,Janowska, K.,McDowell, S.,Mansouri, K.,Parks, R.,Manne, K.,Stalls, V.,Kopp, M.F.,Henderson, R.,Edwards, R.J.,Haynes, B.F.,Acharya, P.; D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction.; Cell Rep, 34:108630-108630, 2021; PubMed: 33417835; DOI: 10.1016/j.celrep.2020.108630

実験手法

ELECTRON MICROSCOPY (3.21 Å)