7KCT
Crystal Structure of the Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase (OGC) Biotin Carboxylase (BC) Domain Dimer in Complex with Adenosine 5'-Diphosphate Magnesium Salt (MgADP), Adenosine 5'-Diphosphate (ADP, and Bicarbonate Anion (Hydrogen Carbonate/HCO3-)
Summary for 7KCT
Entry DOI | 10.2210/pdb7kct/pdb |
Related | 7KBL 7KC7 |
Descriptor | 2-oxoglutarate carboxylase small subunit, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | biotin carboxylase, biotin-dependent carboxylase, pyruvate carboxylase, atp-grasp, aquificales, rtca, dimer interface, bicarbonate, sequence determining positions, structural waters, thermophile, carbon fixation, thermophilic protein, dimer, wet interface, ligase |
Biological source | Hydrogenobacter thermophilus |
Total number of polymer chains | 2 |
Total formula weight | 111173.39 |
Authors | Buhrman, G.K.,Rose, R.B.,Enriquez, P.,Truong, V. (deposition date: 2020-10-07, release date: 2021-01-27, Last modification date: 2023-10-18) |
Primary citation | Buhrman, G.,Enriquez, P.,Dillard, L.,Baer, H.,Truong, V.,Grunden, A.M.,Rose, R.B. Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase. Biochemistry, 60:324-345, 2021 Cited by PubMed: 33464881DOI: 10.1021/acs.biochem.0c00815 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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