7KCT

Crystal Structure of the Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase (OGC) Biotin Carboxylase (BC) Domain Dimer in Complex with Adenosine 5'-Diphosphate Magnesium Salt (MgADP), Adenosine 5'-Diphosphate (ADP, and Bicarbonate Anion (Hydrogen Carbonate/HCO3-)

7KCT の概要

• エントリーDOI: 10.2210/pdb7kct/pdb
• 関連するPDBエントリー: 7KBL 7KC7
• 分子名称: 2-oxoglutarate carboxylase small subunit, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: biotin carboxylase, biotin-dependent carboxylase, pyruvate carboxylase, atp-grasp, aquificales, rtca, dimer interface, bicarbonate, sequence determining positions, structural waters, thermophile, carbon fixation, thermophilic protein, dimer, wet interface, ligase
• 由来する生物種: Hydrogenobacter thermophilus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 111173.39

構造登録者

Buhrman, G.K.,Rose, R.B.,Enriquez, P.,Truong, V. (登録日: 2020-10-07, 公開日: 2021-01-27, 最終更新日: 2023-10-18)

• 主引用文献: Buhrman, G.,Enriquez, P.,Dillard, L.,Baer, H.,Truong, V.,Grunden, A.M.,Rose, R.B.; Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.; Biochemistry, 60:324-345, 2021; PubMed: 33464881; DOI: 10.1021/acs.biochem.0c00815

実験手法

X-RAY DIFFRACTION (2.02 Å)