7KCN
Reconstructed ancestor of HIUases and Transthyretins
Summary for 7KCN
Entry DOI | 10.2210/pdb7kcn/pdb |
Related | 7KJJ |
Descriptor | HIUase-TTR ancestor, 1,2-ETHANEDIOL, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | unknown function, probably a 5-hydroxyisourate hydrolase |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 27990.21 |
Authors | Nagem, R.A.P.,Bleicher, L.,Costa, M.A.F. (deposition date: 2020-10-06, release date: 2021-05-19, Last modification date: 2024-05-22) |
Primary citation | Carrijo de Oliveira, L.,Figueiredo Costa, M.A.,Goncalves Pedersolli, N.,Heleno Batista, F.A.,Migliorini Figueira, A.C.,Salgado Ferreira, R.,Alves Pinto Nagem, R.,Alves Nahum, L.,Bleicher, L. Reenacting the Birth of a Function: Functional Divergence of HIUases and Transthyretins as Inferred by Evolutionary and Biophysical Studies. J.Mol.Evol., 89:370-383, 2021 Cited by PubMed: 33956179DOI: 10.1007/s00239-021-10010-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
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