7KAM

Cryo-EM structure of the Sec complex from T. lanuginosus, wild-type, class with Sec62, plug-closed conformation

Summary for 7KAM

Entry DOI	10.2210/pdb7kam/pdb
EMDB information	22775
Descriptor	Protein transport channel Sec61 complex, alpha subunit (Sec61), Protein transport channel Sec61 complex, gamma subunit (Sss1), Protein transport channel Sec61 complex, beta subunit (Sbh1), ... (7 entities in total)
Functional Keywords	sec61, translocon, endoplasmic reticulum, protein translocation, sec62, sec63, channel, protein transport
Biological source	Thermomyces lanuginosus More
Total number of polymer chains	7
Total formula weight	248145.17
Authors	Itskanov, S.,Park, E. (deposition date: 2020-10-01, release date: 2021-01-06, Last modification date: 2024-03-06)
Primary citation	Itskanov, S.,Kuo, K.M.,Gumbart, J.C.,Park, E. Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62. Nat.Struct.Mol.Biol., 28:162-172, 2021 Cited by PubMed: 33398175 DOI: 10.1038/s41594-020-00541-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation