7KAM

Cryo-EM structure of the Sec complex from T. lanuginosus, wild-type, class with Sec62, plug-closed conformation

7KAM の概要

• エントリーDOI: 10.2210/pdb7kam/pdb
• EMDBエントリー: 22775
• 分子名称: Protein transport channel Sec61 complex, alpha subunit (Sec61), Protein transport channel Sec61 complex, gamma subunit (Sss1), Protein transport channel Sec61 complex, beta subunit (Sbh1), ... (7 entities in total)
• 機能のキーワード: sec61, translocon, endoplasmic reticulum, protein translocation, sec62, sec63, channel, protein transport
• 由来する生物種: Thermomyces lanuginosus; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 248145.17

構造登録者

Itskanov, S.,Park, E. (登録日: 2020-10-01, 公開日: 2021-01-06, 最終更新日: 2024-03-06)

• 主引用文献: Itskanov, S.,Kuo, K.M.,Gumbart, J.C.,Park, E.; Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.; Nat.Struct.Mol.Biol., 28:162-172, 2021; PubMed: 33398175; DOI: 10.1038/s41594-020-00541-x

実験手法

ELECTRON MICROSCOPY (3.8 Å)