7K9Z

Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52

7K9Z の概要

• エントリーDOI: 10.2210/pdb7k9z/pdb
• 分子名称: 52 Fab Heavy Chain, 52 Fab Light Chain, 298 Fab Light Chain, ... (6 entities in total)
• 機能のキーワード: sars-cov-2, receptor binding domain, neutralizing antibodies, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 120012.92

構造登録者

Newton, J.C.,Kucharska, I.,Rujas, E.,Cui, H.,Julien, J.P. (登録日: 2020-09-29, 公開日: 2020-10-28, 最終更新日: 2023-10-18)

• 主引用文献: Rujas, E.,Kucharska, I.,Tan, Y.Z.,Benlekbir, S.,Cui, H.,Zhao, T.,Wasney, G.A.,Budylowski, P.,Guvenc, F.,Newton, J.C.,Sicard, T.,Semesi, A.,Muthuraman, K.,Nouanesengsy, A.,Aschner, C.B.,Prieto, K.,Bueler, S.A.,Youssef, S.,Liao-Chan, S.,Glanville, J.,Christie-Holmes, N.,Mubareka, S.,Gray-Owen, S.D.,Rubinstein, J.L.,Treanor, B.,Julien, J.P.; Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.; Nat Commun, 12:3661-3661, 2021; PubMed: 34135340; DOI: 10.1038/s41467-021-23825-2

実験手法

X-RAY DIFFRACTION (2.95 Å)