7K9H

SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)

7K9H の概要

• エントリーDOI: 10.2210/pdb7k9h/pdb
• 関連するPDBエントリー: 7K9I 7K9J 7K9K
• EMDBエントリー: 22748 22749 22750 22751 22752 22753
• 分子名称: Spike glycoprotein, 2B04 heavy chain, 2B04 light chain, ... (8 entities in total)
• 機能のキーワード: sars-cov-2, neutralizing antibody, ace2-competitive, receptor-binding domain, viral protein-immune system complex, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 488471.94

構造登録者

Errico, J.M.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2020-09-29, 公開日: 2021-09-29, 最終更新日: 2021-11-10)

• 主引用文献: Errico, J.M.,Zhao, H.,Chen, R.E.,Liu, Z.,Case, J.B.,Ma, M.,Schmitz, A.J.,Rau, M.J.,Fitzpatrick, J.A.J.,Shi, P.Y.,Diamond, M.S.,Whelan, S.P.J.,Ellebedy, A.H.,Fremont, D.H.; Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.; Cell Rep, 37:109881-109881, 2021; PubMed: 34655519; DOI: 10.1016/j.celrep.2021.109881

実験手法

ELECTRON MICROSCOPY (3.2 Å)