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7K8W

Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119

Summary for 7K8W
Entry DOI10.2210/pdb7k8w/pdb
EMDB information22729 22730 22731 22732 22733 22734 22735 22736 22737
DescriptorSpike glycoprotein, C119 Fab Heavy Chain, C119 Fab Light Chain, ... (5 entities in total)
Functional Keywordssars-cov-2, spike glycoprotein, covid-19, monoclonal antibody, neutralizing antibody, protein-immune system complex, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains7
Total formula weight529969.42
Authors
Sharaf, N.G.,Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-09-27, release date: 2020-10-21, Last modification date: 2021-01-13)
Primary citationBarnes, C.O.,Jette, C.A.,Abernathy, M.E.,Dam, K.A.,Esswein, S.R.,Gristick, H.B.,Malyutin, A.G.,Sharaf, N.G.,Huey-Tubman, K.E.,Lee, Y.E.,Robbiani, D.F.,Nussenzweig, M.C.,West Jr., A.P.,Bjorkman, P.J.
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588:682-687, 2020
Cited by
PubMed: 33045718
DOI: 10.1038/s41586-020-2852-1
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.6 Å)
Structure validation

217705

數據於2024-03-27公開中

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