7K8W

Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119

7K8W の概要

• エントリーDOI: 10.2210/pdb7k8w/pdb
• EMDBエントリー: 22729 22730 22731 22732 22733 22734 22735 22736 22737
• 分子名称: Spike glycoprotein, C119 Fab Heavy Chain, C119 Fab Light Chain, ... (5 entities in total)
• 機能のキーワード: sars-cov-2, spike glycoprotein, covid-19, monoclonal antibody, neutralizing antibody, protein-immune system complex, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 529969.42

構造登録者

Sharaf, N.G.,Barnes, C.O.,Bjorkman, P.J. (登録日: 2020-09-27, 公開日: 2020-10-21, 最終更新日: 2021-01-13)

• 主引用文献: Barnes, C.O.,Jette, C.A.,Abernathy, M.E.,Dam, K.A.,Esswein, S.R.,Gristick, H.B.,Malyutin, A.G.,Sharaf, N.G.,Huey-Tubman, K.E.,Lee, Y.E.,Robbiani, D.F.,Nussenzweig, M.C.,West Jr., A.P.,Bjorkman, P.J.; SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.; Nature, 588:682-687, 2020; PubMed: 33045718; DOI: 10.1038/s41586-020-2852-1

実験手法

ELECTRON MICROSCOPY (3.6 Å)